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What is Macular Degeneration?

Macular degeneration, or age-related macular degeneration (AMD), is a disease of the center part of the retina called the macula. The macula controls our central vision and enables us to see fine details clearly. It is what allows us to read, drive a car, and recognize faces or colors.

The precise factors that cause macular degeneration are not specifically known; however, as people get older, the chances for developing eye disease increases. In fact, AMD is the leading cause of blindness for Americans over the age of 60.

Macular degeneration usually affects both eyes; however, the severity of the disease can differ greatly between the two eyes. In some cases, AMD can advance so slowly that people notice little change in their vision. In others, the disease can progress so fast that it can lead to a loss in vision in both eyes. With this in mind, macular degeneration occurs in two forms: dry and wet.

Dry Macular Degeneration

Dry macular degeneration is the more common form of AMD. It is the slow advancing form that occurs when the light-sensitive cells in the macula begin to gradually break down. As more of these cells continue to break down, central vision becomes blurrier. In its advanced stages, dry AMD can cause a dark blurred spot in the center of your vision.

Wet Macular Degeneration

Wet macular degeneration differs from dry macular degeneration in that it involves the growth of abnormal blood vessels underneath the macula. Wet AMD occurs aggressively and exists only in the advanced stage of macular degeneration. Because of this, the wet form leads to significantly more vision loss than the dry form.

Dry AMD can turn into wet AMD. In fact, all people who have wet AMD had the dry form at one point, but dry AMD does not necessarily have to progress into the wet form. Currently, there is no certain way to predict if or when dry AMD will turn into wet AMD.

What are Common Symptoms of Macular Degeneration?

Neither dry nor wet macular degeneration causes any eye pain. Symptoms of dry AMD progress gradually and usually do not end in total blindness. Blurred vision is the first symptom that you may start to notice. Tasks such as driving, reading, and even recognizing people’s faces may start to because more difficult as your macular degeneration worsens. In the advanced stages, a large area of grey blocking your central vision may start to develop. People can often have completely obscured central vision, but still have clear peripheral vision.

The same symptoms mentioned above are also encountered in wet macular degeneration. In addition, the most common symptom in wet AMD is straight lines appearing crooked or wavy. This occurs in wet AMD because blood vessels under the macula begin to leak and lift the macula, causing a distortion in your vision.

Your doctor may give you something called an Amsler Grid to monitor the progression of your macular degeneration. This grid is a pattern that resembles a checkerboard. You will be asked to cover one eye and stare at a black dot in the center. You may notice that the straight lines in the pattern appear wavy or even missing.

This distortion in the Amsler grid is abnormal and may indicate the beginning of wet macular degeneration. There is no permanent cure for either dry or wet macular degeneration. However, there are treatment therapies that can delay the progression of AMD.

Amsler Grid

Retinal Injections

The most common treatment to slow down the progression of wet macular degeneration is the injection of drugs into the eye. These drugs inhibit the growth of new blood vessels. Dilated eye examinations are required to keep a close observation of the macula’s response to the medication.

These examinations can be as frequent as every month, and injections may be repeated over the course of this time depending on the effectiveness of the treatment. With retinal injections, visual loss can be slowed or even halted, and some patients may even experience some improvement of vision.

Laser Treatments

Lasers can also be used to treat wet macular degeneration. During laser treatment, a high energy light beam is directed at new and leaky blood vessels in order to completely destroy them. However, the laser beam may also destroy surrounding healthy tissue and because of this, laser treatments are usually less favored over injections.


The National Eye Institute’s Age-Related Eye Disease Study (AREDS) found that taking a specific formulation of antioxidants and zinc significantly reduces the risk of vision loss from advanced AMD. Studies show that these vitamins were most beneficial for people who had intermediate dry AMD in one or both eyes and for people with advanced AMD (either wet or dry) in only one eye.

Unfortunately, studies have not shown any proof that people with early-stage dry AMD benefit from taking AREDS formulation. It is important to understand that AREDS therapy may only delay the onset of advanced macular degeneration. It is not a cure and it cannot restore vision already lost by the disease.

Living with Macular Degeneration

The idea of life with age-related macular degeneration can be upsetting upon the first diagnosis due to the fact that there is no cure for this disease. Despite the danger of this disease, patients rarely lose all of their vision from macular degeneration.

In most cases, poor central vision is a problem but functioning with normal daily tasks is possible. If you feel that you may be experiencing any of the warning signs of macular degeneration mentioned above, our office is willing to offer you not only medical consultation but also emotional support. Our doctors will discuss your options and attempt to prevent permanent vision loss.

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